Audirvana + Rme Adi-2 dac filters

My mac mini with Audirvana 3.5 is connected with the Adi-2 dac from RME. This dac has filters ( NOS, Sharp, Slow, etc. When using one of these filters have I disconnect in Audirvana all filtering by Isotope?
Regards, Syrinx

These are completely different filters. RME filters are inside dac chip (hardware). Audirvana filters are inside program (software). So you can use all of them together.

Thank you, Tony. I will try Audirvana’s izotope filter combined with Adi 2 dac and listen if I hear a difference with the setting without izotope