When I start Audirvana Origin, I have to open the Local Network settings first from within the Mac OS system settings, to put Audirvana off and on again, and then restart Audirvana. I guess this is an MaC OS problem? Who knows and is there a cure?
Have you tried to turn it off in your picture…
then close Origin.
Restart your Mac
without opening origin at startup
remove it if it is in your login items for one time.
Go back to that local network window and allow Origin back,
Open Origin, play a song, it should not ask again.
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I still have exactly the same issue albeit it is less frequent now with 15.4.1 than earlier versions of Sequoia. It is 100% a Sequoia issue. After first starting up if access is denied I go to Local network, then toggle off and on any one of the application entries, it does not need to be the Audirvana entry…. then go to Audirvana and just click the network refresh button and all endpoints re-appear. All will then be good until I shut down the Mac. On a restart the issue will then sometimes re-occur. not always but about every one in three restarts.
It seems to be when the Mac first starts something in the network handshake when the Mac connects to wireless that sometimes prevents local network access being turned on. I wonder whether in my case it is possibly caused by using WiFi 7. Macs do not yet support WiFi 7 so maybe they are not overly focussed on compatibility yet…… who knows.
Some people using Roon are also still reporting issues so not Audirvana specific.
Worth giving @RunHomeSlow suggestions a go but in my case has not resolved the issue.
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I’m on 15.5b2 pref stick always. Did the test with what i wtote, still stick 
Doesn’t seems to work right now, but I will try again.
It’s indeed a Sequoia issue, but what is Audirvana (Antoine/Damien) doing about it?
Probably the same as the rest of us, filing bug reports then hoping for a full fix. Apple are aware that they still have issues with the network stack in Sequoia but Apple Intelligence and Siri woes are the priority.
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It’s crazy to have this kind of problems with each new version of Mac OS, year after year. They should delay new versions to 2, or even 3 years and leave us in peace!
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To be fair, my issues with Sequoia are limited. They made some changes to the network stack very late in the Beta process for macOS 15 (in the release candidate) and poorly documented them. This led to the very significant networking problems some people had with 15.0. Since then playing catch up (and generally failing) with Apple Intelligence and the pathetic Siri have hampered the speed of fixing other bugs in the software.
Would love to see them take a year off and just fix bugs as they did with the Snow Leopard release. Unfortunately a major UI revamp is slated for macOS 16 which will be previewed at WWDC in June and the next beta process will start so I only expect the situation to drag on for a significant time…
Just for information 15.4.1 seemed to resolve this issue for me. Not had a repeat. Currently running the release candidate of 15.5.0 with also no issues.
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