Yes, that’s what I’ve been doing. So far I have tried Windows, Fedora, Xubuntu, ArcoLinux (Arch-based distro) desktop, Ubuntu Server, and Arch install without GUI (in ascending order of preference) on exactly the same hardware. Others have had different preferences or hear no difference.
This is of course to be expected, and it’s interesting to hear from others about what OSs or tweaks of those OSs sound best to them. There are always good ideas to be had from such exchanges. 